Study effect of consumption of green tea extract tablets for amelioration of iron overload and oxidative stress in transfusion-dependent thalassemia patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211118002

Enrollment

Registered

2021-11-18

Start date

2021-11-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thalassemia patients Thalassemia, antioxidant

Interventions

Placebo,Green tea extract 50 mg,Green tea extract 100 mg

Placebo Comparator Dietary Supplement,Active Comparator Dietary Supplement,Active Comparator Dietary Supplement

Eligibility

Sex/Gender

All

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Thalassemia patinets age 15-60 year old

Exclusion criteria

Exclusion criteria: Pregnancy and Lactation

Design outcomes

Primary

Measure	Time frame
Iron status parameters 2 month Serum NTBI LPI ferritin,Oxidetive stress 2 months Red blood cell free radicals, Serum thiobarbituric acid , Serum antioxidant capacity, 4)Serum reduced glutathione (GSH) concentration, 5)Serum catechin (EGCG) concentrations	—

Secondary

Measure	Time frame
Iron status parameters 2 months Serum NTBI, LPI, ferritin,Oxidative stress 2 months Red blood cell free radicals, Serum thiobarbituric acid , Serum antioxidant capacity, 4) Serum reduced glutathione (GSH) concentration, 5) Serum catechin (EGCG) concentrations	—

Countries

Thailand

Contacts

Public ContactSomdet Srichairatanakool

Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200 Thailand

somdet.s@cmu.ac.th0810353463

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026