PREdiction and PREvention of Diabetes using Metformin or Lifestyle Intervention with Economic Evaluation Research

Status

Unknown

Phases

Phase 1Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211116001

Enrollment

520

Registered

2021-11-16

Start date

2021-12-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prediabetes Prediabetes, diabetes, impaired fasting glucose, impaired glucose tolerance, gut microbiota

Interventions

Diabetes routine care from doctor very 4 months for 3 years,participants will get advice for life style modification, behavioral tracking via IoT mobile application for 3 years,participants will take

No Intervention Other,Active Comparator Behavioral,Active Comparator Drug,Active Comparator Other

Routine care,IoT-assisted life style modification,Metformin,IoT-assisted life style modification with metformin

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: prediabetic patients who has either FPG 100-125 mg/dL, 2 h OGTT 140-199 mg/dL, or HbA1C 5.7-6.4%

Exclusion criteria

Exclusion criteria: Diabetic patients Pregnancy HIV infection patients with ASCVD LBBB CHF NY class > II CKD hepatitis weight loss > 10% in 6 months

Design outcomes

Primary

Measure	Time frame
conversion to diabetes 3 years rate of conversion to diabetes	—

Secondary

Measure	Time frame
factors that associated with conversion to diabetes 3 years association	—

Countries

Thailand

Contacts

Public ContactMayuree Homsanit

Faculty of Medicine Siriraj hospital

mayuree.hom@mahidol.ac.th024197284

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026