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Comparison of pruritus incidence after intrathecal morphine 0.1 and 0.2 milligrams in cesarean section, a randomized clinical trial

Comparison of pruritus incidence after intrathecal morphine 0.1 and 0.2 milligrams in cesarean section, a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20211115002
Enrollment
138
Registered
2021-11-15
Start date
2021-05-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pruritus&#44

Interventions

Administer 10&#45
15 mg of 0.5% hyperbaric bupivacaine plus morphine 0.1 mg will be injected as the assignment. ,Administer 10&#45
15 mg of 0.5% hyperbaric bupivacaine plus morphine 0.2 mg will be injected as the assignment.
Experimental Drug,Experimental Drug

Sponsors

Faculty of Medicine, Khon Kaen University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria - Non - emergency - Full term pregnancy - Non - complicated pregnant schedule for cesarean section - Age 18 - 45 years - ASA classification I - III

Exclusion criteria

Exclusion criteria: Exclusion criteria - Contraindicated to spinal anesthesia and study drugs protocol - Refuse to participate the project - BMI is more than 40 kg/m2 - History of pleuritogenic systemic disease, itchy skin disease or using antihistamine or antipruritus within 3 days prior to cesarean section

Design outcomes

Primary

MeasureTime frame
the incidence of pruritus needed treatment every 6 h until 24 hoursafter spinal anesthesia 24 hours post operation Pruritus scale

Secondary

MeasureTime frame
Time to first treatment and score of pruritus, nausea/ vomiting, and pain 24 hours post operation Pruritus , nausea/vomiting and pain analog scale

Countries

Thailand

Contacts

Public ContactNatpapat Tangpraphachaikul

Faculty of Medicine, Khon Kaen University

natpapat.t@gmail.com0814854482

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026