Efficacy of Lidocaine Spray and Paracervical Block for Pain Relief during Manual Vacuum Aspiration in First Trimester Abortion: A non-inferiority Randomized Trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211114001

Enrollment

100

Registered

2021-11-14

Start date

2021-06-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To compare the effectiveness between lidocaine spray and paracervical block as anesthetic procedure in first trimester surgical abortion. lidocaine spray, first trimester abortion, manual vacuum aspiration, pain

Interventions

2 puffs of 10% lidocaine spray at cervix ,a 10 ml of 1% lidocaine injection around the cervico vaginal junction at 4 and 8 o clock

Active Comparator Drug,Sham Comparator Drug

Lidocaine Spray,Lidocaine Injection

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: aged 18 years old or older first trimester abortion at gestational age lower than 12 weeks desire for surgical abortion by manual vacuum aspiration under local anesthesia no previous lidocaine hypersensitivity no history of chronic pelvic pain a confirmed pregnancy by ultrasound informed consent was obtained

Exclusion criteria

Exclusion criteria: unstable vital signs septic abortion pelvic inflammatory disease coagulopathy herbal use anticoagulant or antiplatelet drug use inability to evaluate visual analog scale

Design outcomes

Primary

Measure	Time frame
VAS 1 year chi-square	—

Secondary

Measure	Time frame
side effects 1 year chi-square	—

Countries

Thailand

Contacts

Public ContactPreeyanuch Saelim

Bhumibol Adulayadej Hospital

saelimpreeyanuch@gmail.com0894430184

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026