Mechanical versus Bag-Valve Ventilation During Cardiopulmonary Resuscitation in the Emergency Department: a Randomized Trial

Mechanical versus Bag-Valve Ventilation During Cardiopulmonary Resuscitation in the Emergency Department: a Prospective Randomized Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211113002

Enrollment

Registered

2021-11-13

Start date

2021-12-04

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac arrest Ventilation Mechanical ventilation Mechanical ventilator Bag-valve ventilation Cardiopulmonary resuscitation Cardiac arrest Ventilation Oxygen Emergency department

Interventions

The patients will be connected to a mechanical ventilator (HAMILTON-C1, version SW 2.2.x, Hamilton Medical, Bonaduz, Switzerland), as soon as the patients have been intubated at the ED. Ventilator set

Active Comparator Device,Active Comparator Device

Mechanical ventilation,Bag-valve ventilation

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Adult patients aged 18 years and older who presented with cardiac arrest 2. Whom CPR leader were emergency physician or emergency medicine resident in the emergency department of Srinagarind hospital, Faculty of Medicine, Khon Kaen University.

Exclusion criteria

Exclusion criteria: 1. The patient whom endotracheal intubation cannot be performed before the RO 2. The patient whom ABG cannot be obtained before the ROSC 3. Traumatic cardiac arrest patient 4. Patient who intubated before arriving emergency department 5. The patient with Do Not Resuscitate (DNR) order 6. The patient with sign of irreversible death 7. The patient who suspected of COVID -19 infection 8. The patient who suspected of pneumothorax 9. Pregnant patient

Design outcomes

Primary

Measure	Time frame
arterial oxygen 4-10 minutes after intubation arterial blood gases	—

Secondary

Measure	Time frame
other arterial blood gases parameter 4-10 minutes after intubation arterial blood gases ,ROSC after termination of resuscitation ROSC rate,survival admission, 24 hours, 28 days, hospital discharge survival rate,survival with good neurological outcome hospital discharge survival with good neurological outcome rate,safety and complication after ROSC chest X-ray	—

Countries

Thailand

Contacts

Public ContactThanat Tangpaisarn

Department of emergency medicine, Khon Kaen university

thantan@kku.ac.th0896199907

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026