Identification of specific volatile organic compound (VOCs) in exhaled breath to distinguish pancreatic ductal adenocarcinoma, pancreatic cystic neoplasm and patients without pancreatic-lesion

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20211109002

Enrollment

144

Registered

2021-11-09

Start date

2021-11-09

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic ductal adenocarcinoma Intraductal Papillary Mucinous Neoplasm Volatile organic compound Exhaled breath Pancreatic adenocarcinoma Intraductal papillary mucinous neoplasm ,IPMN Volatile organic compound Exhaled breath - Alveolar air

Interventions

1.Age above or equal 18 years 2.Confirmed diagnosis of PDAC by imaging and tissue diagnosis 2.1Imaging- CT, MRI, EUS 2.2 Tissue - FNA, cytology, Biopsy,1.Age above or equal 18 years 2.Confirmed diagno

Diagnostic,Diagnostic,Diagnostic

PDAC, Cystic neoplasm group,No-pancreatic lesion group

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: PDAC group : 1.Age>= 18 years 2.Confirmed diagnosis of PDAC by imaging and tissue diagnosis 2.1Imaging : CT, MRI, EUS 2.2 Tissue : FNA, cytology, Biopsy Cystic neoplasm group: 1.Age>= 18 years 2.Confirmed diagnosis of IPMN by imaging : CT, MRI, EUS No-pancreatic lesion group : 1.Age>= 18 years (age and sex matched with PDAC) 2.Without any pancreatic lesion confirmed with imaging 3.No history of previous pancreatitis

Exclusion criteria

Exclusion criteria: Concurrent or previous history of 2nd malignancy Previous treatment of PDAC Unable to breath through mouth or nose Pregnancy Concurrent active infection

Design outcomes

Primary

Measure	Time frame
Volatile organic compound pre-treatment TD-GC/FAIMS	—

Secondary

Measure	Time frame
Relationship of Amount of Volatile organic compounds to staging and sizing pre-treatment TD-GC/FAIMS	—

Countries

Thailand

Contacts

Public ContactNuttanit Pungpipattrakul

Division of Gastroenterology, Department of Internal Medicine, King Chulalongkorn Memmorial Hospital, Bangkok, Thailand

pung.dung.foui@gmail.com0896551085

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026