High-intensity strength exercises and nutrition supplementation for sarcopenic older adults

The effects of progressive resistance exercise and nutrition supplementation on muscle mass, strength and physical performance in older Malaysian adults with sarcopenia: A randomised-controlled trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211102007

Enrollment

Registered

2021-11-02

Start date

2019-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia in older adults Sarcopenia Older adults Muscle mass Muscle strength

Interventions

Older adults diagnosed as having sarcopenia or pre-sarcopenia are given high-intensity resistance training along with nutrition supplementation as the experimental group for a total of 12 weeks. ,Olde

Experimental Other,Active Comparator Other

Progressive high-intensity resistance training and nutrition supplementation,Nutrition supplementation

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: Criteria needed for you to be eligible for this study are: - Men and women aged 60 years and above - Body mass index <33 kg/m2 - Have not participated in any sport training programme for more than 3 times a week and more than 30 min/day for the past one year - Have not participated in any resistance training in the past two years - Cleared initial screening with PAR-Q+ - Skeletal muscle index: <8.5 kg/m2 for men, <5.7 kg/m2 for women - Hand grip strength: <30 kg for men, <18 kg for women OR gait speed <0.8 m/s for both men and women - Physically-abled to participate in exercises

Exclusion criteria

Exclusion criteria: You will not be able to join this study if you are - Diagnosed with any unstable coronary heart disease, congestive heart - disease, chronic obstructive pulmonary disease, diabetes mellitus, renal failure - Having uncontrolled hypertension - Presented with major orthopaedic disability - Presented with silent ischaemia from sub-maximal exercise test - Smoking - Daily alcohol consumption

Design outcomes

Primary

Measure	Time frame
Muscle strength After 12 weeks of the intervention kg,Muscle mass After 12-week intervention kg/m squared,Muscle performance or function After 12-week intervention SPPB scores	—

Secondary

Measure	Time frame
Nutritional status After 12-week intervention MNA scores	—

Countries

Malaysia

Contacts

Public ContactVina Tan

Universiti Sains Malaysia

vina@usm.my6097677538

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026