osteoarthritic knee patients Nalbuphine, triamcinolone, pain intensity, side effects
Conditions
Interventions
normal saline with 40mg. lidocaine,nalbuphine with 40 mg. lidocaine,nalbuphine with 40 mg. lidocaine,Triamcinolone with 40 mg. lidocaine
control ,Nalbuphine 5 mg,Nalbuphine 10 mg.,Triamcinolone 40 mg.
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
50 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients that have been diagnosed with osteoarthritis According to the diagnostic guidelines, the criteria for the diagnosis of osteoarthritis of the American College of Rheumatology include Patients with knee pain and bone replacement from radiography (radiographic osteophytes) with at least 1 of the following: morning stiffness less than 30 minutes or there is a cracking noise (crepitus) in the knee while moving 2. Age less than or equal 65 years. 3. Pain intensity by VAS score equal or more than 5/10
Exclusion criteria
Exclusion criteria: 1. Received systemic administration of analgesics within 24 hours before study 2. Received medication about CNS such as anticonvulsant, tramadol, muscle relaxant, anxiolytic, tranquilizers and antipsychotics 3. Suspected septic knee joint 4. Acute or severe bronchial asthma 5. High risk for gastrointestinal obstruction included paralytic ileus 6. History for allergy nalbuphine 7. Adrenal Insufficiency 8. Epilepsy 9. Pregnancy or lactation 10. Severe hypotension 11. Psychotic disorder 12. Suspected cerebrovascular bleeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity 0,5,10,15,20,25,30,35,40,45,50,55,60 minutes VAS | — |
Secondary
| Measure | Time frame |
|---|---|
| PROM 1 week, 1 month, 2 months, and 3 months WOMAC,PROM 1 week, 1 month, 2 months, and 3 months ROM,first time that patients need analgesic drug 1 day, 1 week, 1month, 2 months, 3 months time,side effect 0,5,10,15,20,25,30,35,40,45,50,55,60 minutes, 1 day, 1 week, 1 month, 2 months, and 3 months symptoms | — |
Countries
Thailand
Contacts
Public Contactbura sindhupakorn
Suranaree University of Technology Institute of Social Technology
Outcome results
None listed