A randomized controlled trial comparing pre-operative abdominal surgery skin preparation with aqueous versus alcoholic Chlorhexidine for surgical site infection prevention

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211028001

Enrollment

1300

Registered

2021-10-28

Start date

2021-11-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal surgery Pre-operative scrub Alcoholic chlorhexidine Aqueous chlorhexidine Surgical site infection Abdominal surgery

Interventions

Using alcoholic base chlorhexidine to pre-operative scrub,Using chlorhexidine in water to pre-operative scrub

Active Comparator Drug,Experimental Drug

Alcoholic chlorhexidine,Aqueous chlorhexidine

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Adult patients who are more than 18 years old. 2. All abdominal surgery, include both laparoscopy and open surgery, from any incision or gastrointestinal pathology 3. Any wound classification 4. American Society of Anesthesiologists (ASA) patient classification < 5.

Exclusion criteria

Exclusion criteria: 1. Potential second-look operation or planned revisionary surgery. 2. Patient who had history of allergy with alcohol. 3. Already participate in the other trials involving abdominal operation. 4. Using prosthetic material in surgical wound 5. Not willing to participate

Design outcomes

Primary

Measure	Time frame
surgical site infection 1 month CDC criteria for SSI	—

Secondary

Measure	Time frame
Wound separation 1 week Clinical examination	—

Countries

Thailand

Contacts

Public ContactSuphakarn Techapongsatorn

Navamindradhiraj University

suphakarn@nmu.ac.th0891268484

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026