Bitten by green pit viper Limb swelling at least to nearest joint No systemic indications for antivenom Snake Bite Snake Envenoming Antivenins Extremities Edema
Conditions
Interventions
Patients enrolled in this arm were received 3 vials of monovalent green pit viper antivenom dissolved in 50 mL of NSS which are slowly dripped IV in 30 minutes.,Patients enrolled in this arm were rece
Active Comparator Drug,Placebo Comparator Drug
Antivenom,Placebo
Sponsors
Siriraj Routine to Research Unit
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Bitten by green pit viper diagnosed by fang mark plus at least one of the followings : bring the bitten snake or describe the characteristics of the snake correctly - Bitten at upper or lower limb and swelling of bitten area up to nearest joint (if bitten at hand, foot, finger, or toe then the swelling area must reach wrist or ankle)
Exclusion criteria
Exclusion criteria: - Having other clear indications for antivenins - Patients taken any antiplatelet or anticoagulant medication - Patients have underlying disease associated with abnormal hemostasis - Patients cannot clearly identified bitten snake as indicated in inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local limb swelling reduction 6 hours after intervention % limb swelling reduction | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain reduction 6 hours after intervention Pain score,Hospital length of stay After discharge Days of hospital,Incidence of hypersensitivity reaction 14 days after intervention Observation,Incidence of wound infection 14 days after intervention Observation | — |
Countries
Thailand
Contacts
Public ContactKorakot Suvanges
Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed