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Comparison of the Immunogenicity of ChAdOx1 nCoV-19 (COVID-19) Vaccine against the Wild-Type and Delta Variant in Kidney Transplant Recipients and Healthy Volunteers

Comparison of the Immunogenicity of ChAdOx1 nCoV-19 (COVID-19) Vaccine against the Wild-Type and Delta Variant in Kidney Transplant Recipients and Healthy Volunteers

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20211025004
Enrollment
200
Registered
2021-10-25
Start date
2021-06-08
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Immune response after ChAdOx1 nCoV-19 Vaccine in kidney transplant patients compared to healthy volunteers. Immune response, ChAdOx1 nCoV-19 Vaccine, kidney transplant patients, Wuhan Strain, B.1.617.2 (Delta) Variant, antibody, T-cell response

Interventions

Kidney transplant patients who received 2 doses of ChAdOx1 nCoV-19 Vaccine,Healthy volunteers who received 2 doses of ChAdOx1 nCoV-19 Vaccine
Prevention,Prevention
Kidney transplant patients,Healthy volunteers

Sponsors

Kao Tun Roke Foundation
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Adult (age >= 18 years old), 2.Kidney transplant recipients, 3. Recipients 2 doses of ChAdOx1 nCoV-19 vaccine

Exclusion criteria

Exclusion criteria: 1. Refuse to participate, 2.Infected with COVID-19 during the study period, 3. Recipients of intravenous immunoglobulin

Design outcomes

Primary

MeasureTime frame
Immunogenicity 2-6 weeks after vaccination Antibody response and T-cell response

Secondary

MeasureTime frame
Associated factors of antibody response After the results of immune response Statistical analysis,Associated factors of T-cell response After the results of immune response Statistical analysis,Safety and adverse reactions after vaccination After completion of each dose of vaccination Statistical analysis

Countries

Thailand

Contacts

Public ContactSiriorn Watcharananan

Praram 9 Hospital

orndoctor@yahoo.com66841108000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026