Efficacy of fractional CO2 vaginal laser treatment of overactive bladder in Postmenopausal women : a double- blinded randomized controlled study

Efficacy of fractional carbondioxide vaginal laser treatment of overactive bladder in Postmenopausal women : a double- blinded randomized controlled study

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211022005

Enrollment

Registered

2021-10-22

Start date

2021-07-21

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postmenopausal women with overactive bladder symptom postmenopausal women , overactive bladder , fractional CO2 vaginal laser

Interventions

Women will receive fractional carbondioxide GYNELASETM INTERmedic Barcelona Spain vaginal laser treatment for laser once a month for three months for a total of three times. , Defined as a procedu

Experimental Device,Sham Comparator Device

fractional carbondioxide vaginal laser ,fractional carbondioxide vaginal laser

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: postmenopausal women with overactive bladder symptom which in woman complained at least 3 months, frequency of micturition on average at least 8 times per 24 hours and at least three episodes of urgency (at least grade 2 by Patient Perception of Intensity of Urgency Scale )

Exclusion criteria

Exclusion criteria: Receive hormone therapy within 6 months Use a moisturizing agent or vaginal lubricant within 30 days. Received drugs to treat overactive bladder (Antimuscarinics or beta 3 adrenoceptor agonists) within 3 months. Botox injections treatment around the bladder over a period of 6 months. Patient having pelvic organ prolapse at level 3 or higher Patients who have contraindications to the use of vaginal carbon dioxide laser therapy. Patients who have brain problems and are able to make decisions for oneself.

Design outcomes

Primary

Measure	Time frame
overactive bladder symptoms at 2 weeks after end of the intervention ICIQ OAB Thai version	—

Secondary

Measure	Time frame
quality of life at 2 weeks after end of the intervention ICIQ OAB Thai version ,side effects of fractional CO2 vaginal laser at 2 weeks after end of the intervention Patient reported outcome using a questionnaire interview	—

Countries

Thailand

Contacts

Public ContactUrogynecology unit Siriraj Hospital

siriraj hospital

toei_sara@hotmail.com6624194782

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026