Methods to improve hearing from idiopathic sudden sensorineural hearing loss Intratympanic steroid, sudden sensorineural hearing loss
Conditions
Interventions
Methylprednisolone 0.4-0.8 ml will be injected at posteroinferior quadrant of tympanic membrane of affected ear weekly for 2 weeks,Prednisolone 1 mg/kg/day is given to the patient continually 7 days
Active Comparator Drug,Active Comparator Drug,Active Comparator Drug,No Intervention Drug
Intratympanic Methylprednisolone,Oral prednisolone,Intratympanic methylprednisolone and oral prednisolone,no intervention
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients who have been diagnosed sudden sensorineural hearing loss by losing pure tone average within 40-70 decibels for at least 3 consecutive frequencies 2.Onset starts within 7 days prior to hospital 4.Must be idiopathic cause 5.Never been treated this condition before 6.Unilateral side 7.can speak Thai
Exclusion criteria
Exclusion criteria: 1. active conditions of external/middle ear disease 2.History of surgery/trauma at head and neck area prior onset of symptom 1 month 3.congenital hearing loss 4.Poor controlled of underlying disease eg. poor controlled DMT2,ESRD 5.History of Meniere disease 6.History of radiotherapy/chemotherapy/ototoxic drugs usage prior onset of symptom 2 weeks 7.underlying retrocochlear pathology 8.active pulmonary tuberculosis/parasitic infestation 9.severe osteoporosis, congestive heart failure, Cushing's syndrome, psychiatric disorders, glaucoma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| level of hearing improvement 2 weeks,4weeks,2months,3months Pure tone audiogram | — |
Secondary
| Measure | Time frame |
|---|---|
| improvement of otological symptoms 2 weeks, 4weeks, 2 months, 3 months Visual analog score | — |
Countries
Thailand
Contacts
Public ContactRawisara Sritrakool
Otorhinolaryngology department
Outcome results
None listed