Women patients under total abdominal hysterectomy or open myomectomy with/without other operations, cystectomy, ovarian tumor removal, Salpingectomy, Salpingo-oophorectomy Paracetamol, tramadol, single oral, combination, open hysterectomy, pain
Conditions
Interventions
a preoperative single oral dose tramadol/paracetamol combination 50/500 mg,a preoperative single oral dose tramadol/paracetamol combination 75/650 mg
Active Comparator Drug,Active Comparator Drug
tramadol/paracetamol combination 50/500 mg,tramadol/paracetamol combination 75/650 mg
Sponsors
Khon Kaen University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. 18-65 year old women, 2. ASA physical status classification 1-2, 3. undergoing open abdominal benign gynecologic condition
Exclusion criteria
Exclusion criteria: 1. History of study drug allergy, 2. History of chronic pain, liver disease or gastrointestinal bleeding, 3. pregnancy, 4. psychiatric problem
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 hr postoperative total morphine consumption 24 hr after operation mg | — |
Secondary
| Measure | Time frame |
|---|---|
| tim to first morphine requirement 24 hr of study minute,Pain severity 24 hr of study Numeric rating scale,Side effect 24 hr of study PONV severity grading,side effect 24 hr of study Sedation score,side effect 24 hr of study ambulation score | — |
Countries
Thailand
Contacts
Public ContactSuparada Piyaphinyophap
Khon Kaen University
Outcome results
None listed