Women who have diagnosis with Primary Dysmenorrhea. Primary Dysmenorrhea Prasaplai Thai herbal medicine Menstruation
Conditions
Interventions
The dosage of Prasaplai for research takes two capsules three times per day before meals beginning on three days before menstruation and two days in menstruation continually 3 months.,The dosage of pl
Experimental Drug,Placebo Comparator No treatment
Prasaplai,Placebo
Sponsors
Agricultural Research Development Agency
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-45 years, 2. Regular menstrual cycle duration is 21 to 35 days, 3. Diagnosed with primary dysmenorrhea, 4. Pain scores higher than or equal 4 out of 10 on Numeric Rating Scales (NRS) lasting for 3 months.
Exclusion criteria
Exclusion criteria: 1. History of allergy to ingredients contained in PSP, starch and mefenamic, 2. Any gynecologic conditions confirmed of other pelvic pathologies by pelvic ultrasonography, 3. Placement of intrauterine devices, 4. Other abdominal surgery in 1 year or medical history which can cause abdominal pain such as gallbladder, gallstone, dyspepsia, or irritable bowel syndrome, 5. Using of any kind of analgesic drugs, medications, hormones, or supplementary medicines, 6. Breastfeeding period, pregnant or likely to become pregnant within the next 6 months, 7. Blood transfusion within the last 3 months, 8. Smoking, alcoholism, or drug abuse, 9. Abnormal liver and renal functions with symptoms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain score every month, continually 3 months after intervention NRS | — |
Secondary
| Measure | Time frame |
|---|---|
| Safty screening, after intervention every month (3 months), and follow up Blood chemistry,Metabolomic profile screening, after intervention every month (3 months), and follow up Compound | — |
Countries
Thailand
Contacts
Public ContactDarat kanlayananthaphecha
Mahidol University
Outcome results
None listed