Effects of an isotonic balanced crystalloid solution on hyponatremia in cardiac surgery

Effects of an isotonic balanced crystalloid solution and acetated Ringers solution on the incidence of hyponatremia in patients who have cardiac surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211006001

Enrollment

260

Registered

2021-10-06

Start date

2016-08-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients aged between 18 and 70 years with cardiac disease who underwent cardiac surgery procedures Isotonic balanced crystalloid, hyponatremia, hyperchloremia, cardiac surgery

Interventions

Isotonic balanced crystalloid solution,Balanced crystalloid solution

Experimental Drug,Experimental Drug

Sterofundin,Acetate Ringer solution

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients aged between 18 and 70 years with cardiac disease who underwent cardiac surgery procedures

Exclusion criteria

Exclusion criteria: Preoperative serum sodium concentrations less than 135.0 mmol/L Refusal of study participation Emergency surgery

Design outcomes

Primary

Measure	Time frame
Incidence of hyponatremia at immediate after end of the intervention Plasma sodium level	—

Secondary

Measure	Time frame
Incidence of hyperchloremia at immediate after end of the intervention Plasma chloride level	—

Countries

Thailand

Contacts

Public ContactSunthiti Morakul

Department of Anesthesiology Faculty of Medicine Ramathibodi Hospital, Mahidol University

sunthiti@hotmail.com0818544179

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026