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Comparison of a 1.25 mg/ml intralesional triamcinolone acetonide with combination of a 1.25 mg/ml intralesional triamcinolone acetonide and comedone extraction in healing of inflammatory acnes in moderate-to-severe adult acne: a randomized, split-face controlled trial

Comparison of a 1.25 mg/ml intralesional triamcinolone acetonide with combination of a 1.25 mg/ml intralesional triamcinolone acetonide and comedone extraction in healing of inflammatory acnes in moderate-to-severe adult acne: a randomized, split-face controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210924008
Enrollment
40
Registered
2021-09-24
Start date
2021-10-11
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moderate to severe acne Inflammatory acne, intralesional triamcinolone acetatonide, intralesional corticosteroid

Interventions

The selected inflammatory acnes on an randomized split face were injected with triamcinolone acetonide 1.25 mg/ml then followed by comedone extraction on the first day of research. ,The selected infla
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
intralesional triamcinolone acetonide 1.25 mg/ml plus comedone extraction,intralesional triamcinolone acetonide 1.25 mg/ml

Sponsors

Dermatology unit, department of internal medicine, Chulalongkorn university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. moderate-to-severe acne patients with equally distributed acne papules on both sides of one's face (different papules no more than 5 papules) 2. no prior history of procedure on the papules such as chemical peeling, laser 3. The volunteers have their own cell phones in which the camera's pixel is more than 7 million pixel

Exclusion criteria

Exclusion criteria: 1. allergic to triamcinolone acetonide 2. can't tolerate intralesional procedure and comedone extraction 3. psychiatric problem 4. willing to do other procedures (such as chemical peeling, laser) during the research period (6 month) 5. history of prior keloid and hypertrophic scar

Design outcomes

Primary

MeasureTime frame
healing of inflammatory papule 7 days A numbers of day after the procedures

Secondary

MeasureTime frame
post acne erythema 1, 3, 6 month IQR

Countries

Thailand

Contacts

Public ContactSaranya Srivarasat

Dermatology unit

bellsaranya1992@gmail.com0873588757

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026