Anesthesia induced by a single injection of a short acting intravenous anesthetic may not be adequate of endotracheal intubation as detected by responses of the isolated forearm technique with the incidence up to 19%. The addition of the inhaled sevoflurane may provide adequate depth of anesthesia/analgesia for the intubation. isolated forearm technique depth of anesthesia intubation
Conditions
Interventions
sevoflurane 0.5 MAC administration following intravenous propofol induction,no sevoflurane administration following intravenous propofol induction
additional sevoflurane,no additional sevoflurane
Sponsors
Department of Anesthesilogy, Faculty of Medicine, Chiang Mai University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Surgical patients requiring endotracheal intubation under general anesthesia 2. Isolated forearm technique can be applied 3. ASA PS I-II 4.Inforemed consent
Exclusion criteria
Exclusion criteria: 1. cannot be communicated 2. family history or clinically susceptiple to malignant hyperthermia 3. allergic to propofol or soy bean
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Responses of isolated forearm every 5 minutes before , during and after intubation Pandit scale of isolated forearm responsiveness,depth of anesthesia (qCon) every 1 minutes after induction until complete intubation from starting induction until 0-100,Depth of analgesia (qNOX) every 1 minute after induction until completed intubation 0-100,Recall of intraoperative awareness 48-72 hours postoperatively Brice questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| CVS (Blood pressure, Heart rate every 5 minutes mmHg, beats perminute | — |
Countries
Thailand
Contacts
Public ContactYodying Punjasawadwong
Faculty of Mediicne, Chiang Mai University
Outcome results
None listed