Parturients 18 - 40 year undergoing elective caesarean section under spinal anesthesia postspinal hypotension after spinal anesthesia until delivery Cesarean section Crystalloid Ephedrine Hypotension Spinal anesthesia
Conditions
Interventions
Ringer lactate solution 1L plus ephedrine 10mg intravenous coload,Ringer lactate solution 1L plus normal saline 2 ml intravenous coload
Active Comparator Drug,Placebo Comparator Drug
Sponsors
Faculty of medicine, Khon Kaen University
No study secondary sponsor
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria Parturients aged 18 - 40 year old Singleton pregnancy ,GA 37-42 week ASA II
Exclusion criteria
Exclusion criteria: Exclusion criteria Refuse to participate the project BW < 50 kg History of chronic hypertension or Pregnancy induced hypertension Maternal medical morbidity (cardiovascular,cerebrovascular, chronic disease) contraindication to ephedrine drug
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal hypotension After intrathecal injection of local anesthesia until delivery Repeat blood pressure every 2.5min until delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| intra-operative rescue inotropic drug After intrathecal injection of local anesthesia until delivery Dose of rescue inotropic drug,symptomatic of maternal nausea & vomiting After intrathecal injection of local anesthesia until delivery Episode of symptomatic of maternal nausea & vomiting ,maternal tachycardia After intrathecal injection of local anesthesia until delivery Repeat heart rate every 2.5min until delivery,Apgar scores at the first and fifth minutes After delivery Measurement of Apgar scores at the first and fifth minutes | — |
Countries
Thailand
Contacts
Public ContactPaweena Sutthicharoen
Faculty of medicine, Khon Kaen University
Outcome results
None listed