Clinical Outcomes of Immunohistochemistry of p53 Staining Pattern in High Grade Serous Ovarian carcinoma

Prevalence of p53 immunohistochemistry staining : Retrospective observational study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20210916004

Enrollment

Registered

2021-09-16

Start date

2021-07-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women with high grade serous ovarian cancer High grade serous carcinoma , Ovarian cancer, Immunohistochemical p53 , survival

Interventions

p53 staining more than 60% of tumor cell nuclei.,p53 staining 0% of tumor cell nuclei.,focal p53 staining of tumor cell nuclei.

Treatment,Treatment,Treatment

missense expression patient,Null expression patient,wild type patient

Eligibility

Sex/Gender

Female

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: a total of 62 patients with HGSOC, who underwent primary cytoreductive surgery in Srinagarind Hospital, Faculty of Medicine, Khon Kaen University between January 2016 and December 2020.

Exclusion criteria

Exclusion criteria: The patients who was Incomplete of medical and pathological record and women was diagnosed of HGSOCafter autopsy.

Design outcomes

Primary

Measure	Time frame
prevalence of p53 mutaion 2 months percentage	—

Secondary

Measure	Time frame
associated factor of p53 staining pattern and clinical outcome 2month univaluate and multivariate analysis	—

Countries

Thailand

Contacts

Public Contactpanarat orachum

srinagarind hospital

tt-tang@hotmail.com0819997242

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026