Adapting effective mHealth interventions to improve uptake and adherence of the HIV pre-exposure prophylaxis (PrEP) in Thai young Men who have Sex with Men

Status

Unknown

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20210916003

Enrollment

170

Registered

2021-09-16

Start date

2021-10-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV-uninfected young MSM at risk for acquiring HIV infection, ages 16 to 29 years. HIV, technology-based intervention to promote both motivation to begin PrEP, HIV pre-exposure prophylaxis (PrEP) in Thai young MSM

Interventions

For Aim 1, we will explore barriers and facilitators of PrEP initiation and adherence through (in-person) in-depth interviews with 30 HIV-negative Thai YMSM and 5 clinicians to inform intervention con

suggestions and feedback for intervention delivery captured during interviews in adapting and developing the two components of the intervention (MES-PrEP and MTM). Using the results of the interviews

Active Comparator Behavioral,Active Comparator Behavioral

Aim 1: Adapt MESA to develop MES-PrEP and develop MTM for HIV-negative Thai YMSM,Aim 2: Conduct a pilot RCT to evaluate the feasibility, acceptability, and preliminary efficacy of an intervention comb

Eligibility

Sex/Gender

Male

Age

16 Years to 29 Years

Inclusion criteria

Inclusion criteria: 1) age 16-29 years 2) men who report sex with men in the past 12 months 3) laboratory confirmed HIV negative status 4) self-reported evidence of being at-risk for HIV acquisition, including one of the following in the past 6 months: having a sex with an HIV-positive partner, having anal sex without using a condom, being diagnosed with an STI, or having any illicit drug use (e.g., Amphetamine type stimulants) 5) able to understand, read and speak Thai 6) either having not started PrEP (Group 1: PrEP naive) or currently on PrEP but not adherent to PrEP (taking 3 pills/week) in the past month (Group 2: PrEP users)

Exclusion criteria

Exclusion criteria: 1) in a mutually monogamous relationship of > 6 months with a partner who recently tested HIV-negative 2) a serious cognitive or psychiatric problem that would compromise ability to provide informed consent 3) currently enrolled in another HIV intervention study.

Design outcomes

Primary

Measure	Time frame
MES-PrEP and MTM 12 months Eligibility is the same for both Aim 1 and Aim 2 phases of the study.	—

Secondary

Measure	Time frame
N/A N/A N/A	—

Countries

Thailand

Contacts

Public ContactNitiya Chomchey

Institute of HIV Research and Innovation (IHRI)

nitiya.c@ihri.org082 8994433

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026