Patients with a bilateral impacted mandibular molar that require both osteotomy and odontosection. Mandibular third molar, diclofenac, NSAID, dental pain
Conditions
Interventions
0.1% Diclofenac and collagen sponge in surgical wound.,Collagen sponge PBS in surgical wound.
Experimental Drug,Placebo Comparator No treatment
Diclofenac,Placebo
Sponsors
Faculty of Dentistry, Chiang Mai University , Chiang Mai, Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. The patients aged between 18 to 35 years old. 2. All participants must have a healthy status (ASA I-II according to the classification of the American Society of Anesthesiologists). 3. All participants are patients at an Oral and Maxillofacial surgery clinic, the Faculty of Dentistry, Chiang Mai University who require surgical removal of bilateral impacted mandibular molar that require both osteotomy and odontosection.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or breastfeeding women. 2. History of allergic to diclofenac or other NSAIDs. 3. Patients have any conditions that contraindicated the use of NSAIDs. 4. Patients who used NSAIDs 14 days prior to surgical procedures. 5. History of having ulcers or bleeding in the digestive tract, coagulation disorders or hepatic/renal impairment. 6. Patients who have an infection and/or pericoronitis prior to surgical procedures. 7. Patient who refuses to take any medicine. 8. Patient who is unable to report the collecting data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain intensity when first time pain emerged, then at 6 and 24 hours postoperatively VAS score | — |
Secondary
| Measure | Time frame |
|---|---|
| swelling measurements preoperatively and at the day 2 and day 7 postoperatively facial distances between lower border of tragus to soft tissue pogonion in a millimeters,Trismus measurements preoperatively and at the day 2 and day 7 postoperatively distances between the incisal edges of upper and lower incisors in millimeters,Local adverse effects 1 week after the surgery Incidence rate | — |
Countries
Thailand
Contacts
Public ContactChayarop Supanchart
Chiang Mai University
Outcome results
None listed