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Optimizing an mHealth intervention to improve uptake and adherence of the HIV pre-exposure prophylaxis (PrEP) among Thai young transgender women

Optimizing an mHealth intervention to improve uptake and adherence of the HIV pre-exposure prophylaxis (PrEP) among Thai young transgender women

Status
Unknown
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210914003
Enrollment
200
Registered
2021-09-14
Start date
2021-10-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV pre-exposure prophylaxis (PrEP) among Thai young transgender women PrEP among Thai young TGW

Interventions

Adapt and refine a 2-session mhealth intervention to deliver MES-PrEP and refine YaCool for HIV-negative Thai transgender women aged 18-29. We will recruit 40 HIV negative TGW and 10 healthcare provid
Experimental Other,Experimental Other,Experimental Other
Aim 1 (R21 phase): ,Aim 2 (R33 phase): ,Aim 3.

Sponsors

NIH
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 29 Years

Inclusion criteria

Inclusion criteria: Inclusion: 1. Thai Nationality 2. Age 18-29 years old 3. Male sex at birth 4.Self-identifies as woman or TGW or culturally identifies with the female spectrum 5. Laboratory confirmed HIV negative status 6. Self-reported recent history of condomless sex 7. Either not started PrEP (Group 1: PrEP naive) or currently on PrEP but not adherent (taking 3 pills/week) in the past month (Group 2: PrEP users)

Exclusion criteria

Exclusion criteria: Exclusion: 1. A serious cognitive or psychiatric problem compromising ability to provide informed consent 2. Active suicidal ideation or major mental illness (e.g., untreated psychosis or mania) at the time of interview (patients will be referred for treatment) 3. Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreased creatinine clearance) 4. Currently enrolled in another HIV intervention study

Design outcomes

Primary

MeasureTime frame
Phase IA (R21 Phase) ADAPT-ITT First phase of ADAPT-ITT model. We propose to utilize a qualitative approach to explore PrEP uptake and usage in young TGW. conduct interviews 40 HIV-neg TGW, 10 providers, community health workers.

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactNitiya Chomchey

Institute of HIV Research and Innovation (IHRI)

nitiya.c@ihri.org082 8994433

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026