To prevent postpartum hemorrhage in pregnant women that scheduled for elective cesarean section then oxytocin will be administrated to stimulate uterine contraction. oxytocin intramyometrial intravenous elective cesarean section uterine atony
Conditions
Interventions
Intramyometrial oxyocin administration and intravenous placebo administration,Intravenous oxytocin administration and intramyometrial placebo administration
Experimental Drug,Active Comparator Drug
Intramyometrial oxytocin,Intravenous oxytocin
Sponsors
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.pregnant women who came for elective cesarean section at Siriraj Hospital 2.gestational age at 34 weeks or more
Exclusion criteria
Exclusion criteria: 1. In active phase if labor 2. Hematologic disorder that effect bleeding tendency 3. Contraindication for oxytocin 4. Allergy to oxytocin or its composition 5.Obstetric condition that risk for bleeding such as placenta previa, preeclampsia 6.Fetal anomalies 7. Fetal death 8. Conduct general anesthesia for Cesarean section
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimated blood loss 24 hours postpartum Visual estimation of operative blood loss | — |
Secondary
| Measure | Time frame |
|---|---|
| pregnancy outcomes 7 days Data from chart,Additional uterotonic agent During operative time and 24 hours postpartum Data from intraoperative record,Side effect of oxytocin 24 hours postpartum Interview for known and unknown adverse effects ,Hematocrit 24 hours postpartum Collect blood at 24 hours postpartum and measure for CBC | — |
Countries
Thailand
Contacts
Public ContactPattarawan Limsiri
Faculty of Medicine Siriraj Hospital
Outcome results
None listed