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Effect of Chlorhexidine, Fluoride and Green Tea Oral Gel on Pediatric Salivary Cariogenic Bacteria

Effect of Chlorhexidine, Fluoride and Green Tea Oral Gel on Pediatric Salivary Cariogenic Bacteria

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210913005
Enrollment
71
Registered
2021-09-13
Start date
2017-01-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

salivary S. mutans and Lactobacillus in children Child, Chlorhexidine, Fluoride, Green tea, Streptococcus mutans, Real-time PCR

Interventions

was applied to teeth of children for five minutes before spitting out,was applied to teeth of children for five minutes before spitting out.,was applied to teeth of children for five minutes before sp
green tea 5% gel,chlorhexidine 2% gel ,fluoride 0.2% gel

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 6 Years

Inclusion criteria

Inclusion criteria: Children who were in good physical health with no systemic diseases who had not used antibiotics at least 3 weeks before the study, were included. Other inclusion criteria were the absence of oral soft tissue lesions, any active or severe periodontal disease and no prosthetic or orthodontic appliances. Also, it was confirmed that participants had no history of food or drug allergies and had not used xylitol gums or any type of mouthwash or gel containing fluoride at least 3 weeks before the study.

Exclusion criteria

Exclusion criteria: Children who were in good physical health with no systemic diseases who had not used antibiotics at least 3 weeks before the study, were included. Other inclusion criteria were the absence of oral soft tissue lesions, any active or severe periodontal disease and no prosthetic or orthodontic appliances. Also, it was confirmed that participants had no history of food or drug allergies and had not used xylitol gums or any type of mouthwash or gel containing fluoride at least 3 weeks before the study

Design outcomes

Primary

MeasureTime frame
salivary S. mutans and Lactobacillus before intervention, 30 minutes and one week after intervention Based on laboratory guidelines, samples were stored in a container with ice cubes and transferred to the laboratory for analysis with real-time quantitative Polymerase Chain Reaction).

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Iran

Contacts

Public ContactJelveh Hasheminejad

Resident of Pediatric Dentistry, Department of Pediatric Dentistry, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.

hn.jelveh@gmail.com009834 31325829

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026