Single dose of intravenous paracetamol versus placebo in post-orthognathic surgery pain: A randomized clinical trial

Comparison post orthographic surgery pain in patient with morphine alone and morphine with intravenous paracetamol

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20210908002

Enrollment

Registered

2021-09-08

Start date

2021-09-09

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

orthognathic surgery patients intravenous paracetamol orthognathic surgery

Interventions

Giving intravenous paracetamol 1 gm, 1 dose with morphine,Giving intravenous morphine alone

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. patient undergoing orthognathic surgery 2. ASA classification 1 or 2

Exclusion criteria

Exclusion criteria: 1. Allergy to drug used in the trial. 2. Patient refusal.

Design outcomes

Primary

Measure	Time frame
pain every 4 hour in first 24 hour post operation visual analogue pain score	—

Secondary

Measure	Time frame
morphine consumption and side effect at 24 hour post operation observation	—

Countries

Thailand

Contacts

Public ContactThunshuda Sumphaongern

Faculty of Dentistry, Chulalongkorn university

thunshuda.s@chula.ac.th022188581

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026