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The effectiveness of continuous ultrasound-guided subcostal anterior Quadratus Lumborum Block in patients undergoing laparoscopic Liver resection : a randomized controlled trial

The effectiveness of single-shot ultrasound-guided bilateral anterior quadratus lumborum block with subcostal approach in patients undergoing laparoscopic liver resection: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210908001
Enrollment
50
Registered
2021-09-08
Start date
2021-10-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic liver resection became more popular performing in patients with liver tumors due to comparable several advantages with open liver section. Recently, the use of truncal nerve block combined with intravenous analgesic is the alternative technique to reduce postoperative pain after laparoscopic liver resection. Quadratus lumborum block was developed for perioperative analgesia in hip surgery and lower abdominal surgery.However, the appropriate strategies for postoperative pain manageme

Interventions

Participants will be divided into 2 major treatment groups. Group I (Quadratus lumborum block group): receives ultrasound-guided bilateral anterior quadratus lumborum block with subcostal approach by
Experimental Procedure/Surgery
Single shot ultrasound-guided bilateral anterior quadratus lumborum block with subcostal approach in patients undergoing laparoscopic liver resection

Sponsors

Faculty of Medicine, ChiangMai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. All genders between 18 to 75 years of age 2. Patients with American Society of Anesthesiologists (ASA) physical status classification of I-III 3. Patients subjected to elective laparoscopic liver resection 4. Patients who have given informed consent to participate in this study

Exclusion criteria

Exclusion criteria: 1. Patients with BMI greater than 35 kg/m2 (morbid obesity) 2. Patients with severe obstructive sleep apnea 3. Patients with a history of local anesthetics allergy 4. Patients with skin infection at the injection site of the procedure 5. Patients with any known renal, liver, or heart failure 6. Patients with abnormal coagulation. 7. Patients with daily regular intake of opioid or chronic opioids used 8. Patients who are unable to communicate and cooperate to pain assessment including mental retardation.

Design outcomes

Primary

MeasureTime frame
analgesic efficacy of single-shot ultrasound-guided bilateral anterior quadratus lumborum block with subcostal approach in patients undergoing laparoscopic liver resection at 28-30 months total opioid consumption at 24 hours postoperative

Secondary

MeasureTime frame
treatment efficacy of single-shot ultrasound-guided bilateral anterior quadratus lumborum block with subcostal approach in patients undergoing laparoscopic liver resection at 28-30 months Numerical Rating Scales (NRS)

Countries

Thailand

Contacts

Public ContactNithiwadee Wannawoharn

Department of Anesthesiology, Faculty of medicine, Chiang Mai University

nithiwadee41@gmail.com0825414569

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026