Healthy term pregnant woman Postoperative pain Spinal anesthesia Nalbuphine
Conditions
Interventions
IV PCA nalbuphine,IV PCA morphine
Experimental Drug,Experimental Drug
Nalbuphine group,Morphine group
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Term pregnancy with - Age more than18 years - Patient ASA physical status I-III. - Scheduled for elective cesarean section under spinal anesthesia - Can operate a patient-controlled analgesia (PCA) device.
Exclusion criteria
Exclusion criteria: - Known hypersensitivity to researched drugs - History of chronic pain - History of drug addict use - Patient refuse for spinal anesthesia - Medical complications eg heart diseases, diabetes, hypertension, renal or hepatic disease, obesity >=100 kilograms - Gynecological complications eg myoma uteri, ovarian tumors - Obstetrical complications eg multiple gestation, pre-eclampsia, fetal distress, IUGR(intra-uterine growth retardation), placenta previa
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative morphine and nalbuphine consumption 24 hours milligram | — |
Secondary
| Measure | Time frame |
|---|---|
| Numerical rating scale 6, 12 , 24 hour point,Nausea and vomiting 6,12,24 hour 0-3 point,Pruritus score 6,12,24 hour 0-3 point,Respiratory depression 6 12 24 hour Sedation score 0-3 | — |
Countries
Thailand
Contacts
Public ContactJEDSADAYOOT SAKAROONCHAI
Thammasat University
Outcome results
None listed