Detection of primary cancer and metastatic lesions in patients with HNSCC. Head and Neck Neoplasms 68Ga-FAPI
Conditions
Interventions
Patients with pathologically confirmed head and neck squamous cell carcinoma who were scheduled for PET scan with indication for initial staging or suspected recurrence.
Diagnostic
Head and neck squamous cell carcinoma patients
Sponsors
National Cyclotron and PET Centre, Chulabhorn Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with pathologically confirmed HNSCC 2. Patients who were > 18 years old 3. Patients who were scheduled for PET/CT with indication for initial staging or suspected recurrence
Exclusion criteria
Exclusion criteria: 1. Patients with fasting blood sugar > 150 mg/dL 2. Patients with GFR < 45ml/min 3. Patients with second primary tumor except HNSCC 4. Patients who were pregnant or breast feeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Concordance of FAPI and FDG PET/CT at the time of intervention (PET/CT interpretation) Concordant rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection of primary and metastatic tumor at the time of intervention (PET/CT interpretation) Detection rate,Diagnostic accuracy at the time of intervention (PET/CT interpretation) Sensitivity, specificity, accuracy | — |
Countries
Thailand
Contacts
Public ContactChanisa Chotipanich
National Cyclotron and PET Centre, Chulabhorn Hospital
Outcome results
None listed