post oral cavity surgery in oral cavity cancer patients Oral cavity surgery oral cavity cancer wound healing oral hygiene 0.12% chlorhexidine gluconate (c-20) Normal saline
Conditions
Interventions
0.12% chlorhexidine gluconate(c-20) 30 ml oral irrigation BID for 14 days,normal saline 30 ml oral irrigation BID for 14 days
Active Comparator Drug,Active Comparator Drug
0.12% chlorhexidine gluconate (c-20),normal saline
Sponsors
Ratrchadapiseksompoch fund
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: oral cavity cancer patients oral cavity surgery that has a primary suture and size of the wound more than 2 cm.
Exclusion criteria
Exclusion criteria: American Society of Anesthesiologist(ASA) physical status classification score more than 3 a patient who has the oral mucosal disease a patient who has severe ischemic heart disease, renal disease), connective tissue disease, Liver disease, HIV, Diabetics Mellitus poor control a patient who has coagulation problem or bleeding disorders (Platelet <50,000 or PT, APTT> 1.5x normal control or INR>1.5) allergy to chlorhexidine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparative effectiveness of chlorhexidine gluconate versus normal saline in post oral cavity surgery wound healing of oral cavity cancer patients at 3, 14 days after surgery Wound healing : IPR wound healing scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparative complication of chlorhexidine gluconate versus normal saline in post oral cavity surgery wound healing of oral cavity cancer patients at 3, 14 days after surgery Pain score (VAS) Side effect : irritation/allergy/hypogeusia/brown straining of the dentition | — |
Countries
Thailand
Contacts
Public ContactKarmolchanok Trisirirat
King Chulalongkorn Memorial Hospital
Outcome results
None listed