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Comparison of lactogenic effects of Plook-fire-thatu, Domperidone and Placebo in Postpartum Women: a randomized controlled trial

Comparison of lactogenic effects of Plook-fire-thatu, Domperidone and Placebo in Postpartum Women: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210824005
Enrollment
180
Registered
2021-08-24
Start date
2019-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breastmilk production in healthy postpartum moms who gave birth to a healthy singleton infant. Breast milk, Galactagogues, Herbal medicine, domperidone, Traditional medicine

Interventions

PFT, or Plookfirethatu, was a Thai traditional medicine recipe used to test the lactogenic effect in postpartum women. Its dosage was 270 mg per day, divided into three equal doses per day.,Domperidon
Experimental Drug,Active Comparator Drug,Placebo Comparator Other
PFT,DD,Placebo

Sponsors

Agricultural Research Development Agency
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: postpartum women aged 18 to 45, singleton vaginal birth, good health with no underlying illness, and no history of allergy to phenytoin, propranolol, theophylline, or rifampicin. In order to respond to the questions, they needed to be alert and understand Thai. Her baby's birth weight had to be greater than 2499 grams, and there was no illness that would interfere with breastfeeding

Exclusion criteria

Exclusion criteria: a newborn's postnatal complication requiring intensive care, a drug allergy, and the use of infant formula milk

Design outcomes

Primary

MeasureTime frame
breast milk quantity Three time per day for consecutive three day at postpartum period tested weight method

Secondary

MeasureTime frame
adverse effects consecutive three day at postpartum period fisber scale

Countries

Thailand

Contacts

Public Contactkitti krungkraipetch

Med fac. Burapha Univ., 169 Bangsaen rd. sansuk distr. maung, chonburi, 20131

kitti@go.buu.ac.th038386554

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026