Effect of early and late amniotomy on caesarean section rate and duration of first stage of labor in low-risk pregnancy: A randomized control trial

Effect of amniotomy to caesarean section rate:A Randomized control trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20210818004

Enrollment

132

Registered

2021-08-18

Start date

2021-08-20

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early Vs late amniotomy in low-risk term pregnancy group to caesarean section rate, duration of first stage of labor, maternal outcomes and neonatal outcomes amniotomy caesarean section rate first stage of labor duration

Interventions

early amniotomy: we will perform amniotomy ( breakage of membrane) during cervical dilatation 3-5 cm or bishop score 6 with low-risk term pregnancy,late amniotomy: we will let the membrane break itsel

Experimental Procedure/Surgery,No Intervention No treatment

early amniotomy,late amniotomy or standard care

Eligibility

Sex/Gender

Female

Age

15 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. low-risk pregnancy 2. fetal cephalic presentation 3. presenting to labor room with labor pain 4. cervical dilatation 3-5 cm 5. membrane intact

Exclusion criteria

Exclusion criteria: 1. presenting of any contraindication of amniotomy for example placenta previa, vasa previa 2. fetal anomalies or abnormal Quad test with abnormal karyotype 3. A low-risk pregnancy women with external fetal monitoring category II, III 4. antenatal risk such as GDMA2, PIH, HIV infection

Design outcomes

Primary

Measure	Time frame
caesarean section rate at 26 hours after entering labor room percentage	—

Secondary

Measure	Time frame
duration of first stage of labor at the time when neonatal are born duration of latent phase of labor until fully dilatation of cervix,maternal outcomes observe clinical signs of chorioamnionitis during labor time until neonatal are born, observe umbilical prolapse suddenly after performing amniotomy chorioamnionitis, umbilical cord prolapse, postpartum hemorrhage, puerperal infection,neonatal outcomes after neonatal are born and within 72 hours birth body weight, APGAR score, respiratory support, delayed adaptive, transient tachypnea of newborn, NICU admission, neonatal sepsis, neonatal death	—

Measure

Time frame

duration of first stage of labor at the time when neonatal are born duration of latent phase of labor until fully dilatation of cervix,maternal outcomes observe clinical signs of chorioamnionitis during labor time until neonatal are born, observe umbilical prolapse suddenly after performing amniotomy chorioamnionitis, umbilical cord prolapse, postpartum hemorrhage, puerperal infection,neonatal outcomes after neonatal are born and within 72 hours birth body weight, APGAR score, respiratory support, delayed adaptive, transient tachypnea of newborn, NICU admission, neonatal sepsis, neonatal death

—

Countries

Thailand

Contacts

Public ContactPannathorn Montavichak

Sunpasitthiprasong Hospital

miimumi37@gmail.com0870701001

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026