A pilot study of urine DNA methylation alteration in Non-muscle invasive bladder cancer in Thailand, a potential for diagnosis and surveillance.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20210813003

Enrollment

Registered

2021-08-13

Start date

2021-09-06

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-muscle invasive bladder cancer Non-muscle invasive bladder cancer NMIBC

Interventions

Patients with non-muscle invasive bladder cancer confirmed by pathological tissue from TURBT

Screening

non-muscle invasive bladder cancer group

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Adults older than 18 year-old diagnosed with non-muscle invasive bladder cancer by TURBT with pathologic confirmation

Exclusion criteria

Exclusion criteria: 1. small tissue which cannot be clarified by pathologist 2. benign tumor 3. other tumor apart from urothelial carcinoma 4. muscle invasive bladder cancer 5. prior radiation therapy 6. Previously diagnosed other cancer with prior chemotherapy or radiation therapy

Design outcomes

Primary

Measure	Time frame
Urine DNA methylation genes 1 month after specimen collection DNA methylation CPG hotspot	—

Secondary

Measure	Time frame
Urine DNA methylation genes in Thailand compared to TCGA database 3 months after population data collection ends DNA methylation CPG hotspot	—

Countries

Thailand

Contacts

Public ContactTongtra Watcharawittayakul

King Chulalongkorn Memorial Hospital

researchaffairs@gmail.com022564493

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026