Proton therapy in pediatric brain tumor Proton therapy, CSI, pediatric brain tumor, radiation, radiotherapy
Conditions
Interventions
Pediatric brain tumor patients who require CSI will receive proton beam radiation for CSI and boost
Treatment
Proton CSI
Sponsors
Ratchadapiseksompotch Fund
Eligibility
Sex/Gender
All
Age
1 Years to 15 Years
Inclusion criteria
Inclusion criteria: 1.Thai children 2.Diagnosed with pediatric brain tumor as follows. Embryonal tumor, Medulloblastoma, PNET, ATRT, Pineoblastoma, Ependymoma with intracranial or spinal metastasis, Pure germ cell tumor with intracranial or spinal metastasis, Nongerminomatous germ cell tumor 3. ECOG 0,1,2 4.Receive proton CSI at King Chulalongkorn Memorial Hospital in September 2021 to March 2024
Exclusion criteria
Exclusion criteria: 1.Did not receive maximal safe resection prior to radiation for embryonal tumor and ependymoma. 2. No MRI spine images 3.No CSF cytology report 4. Unable to have follow up visits at King Chulalongkorn Memorial hospital 5. Unable to have sedation during radiation course for non-cooperate patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Toxicitiy During CSI CTCAE score | — |
Secondary
| Measure | Time frame |
|---|---|
| Oncological outcome 3 years after CSI Patients' status death, alive, disease free, recurrence | — |
Countries
Thailand
Contacts
Public ContactChonnipa Nantavithya
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed