Diabetic retinopathy in patients with type 2 diabetes mellitus Diabetic retinopathy, Hyperbaric Oxygen Therapy
Conditions
Interventions
Type 2 DM patients who have scheduled for a course of hyperbaric oxygen therapy,Type 2 DM patients without indication of hyperbaric oxygen therapy who were matched with group 1 patients in terms of di
Treatment,Treatment
Type 2 DM patients who will undergo HBOT,Type 2 DM patients who will not undergo HBOT
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Male or female aged 18 years old of age and above 2. Diagnosed as diabetes mellitus type 2 3. New patients who have indication for hyperbaric oxygen treatment for the first time and will be treated by hyperbaric oxygen 2.4 ATA at least 30 times (90 minutes/time).
Exclusion criteria
Exclusion criteria: 1.Patients cannot be investigated by OCT and others ophthalmological devices. 2.Patients have significant ocular media opacity. 3.Patients used to treated by hyperbaric oxygen. 4.Patients used to undergo surgery vitrectomy. 5.Patients have been treated by focal laser or grid laser before. 6.Pateints have been undergone intraocular surgery , Intravitreous injection and panretinal photocoagulation within 6 months. 7.Patinets have macular diseases which affect results of OCTA. 8.Pateints have uncontrollable cardiovascular diseases such us hypertensive urgency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retinal vessel on OCTA at start of HBOT, at session 11th, 21st, and 30th of HBOT, and at 2 weeks after the end of HBOT OCTA Metrics | — |
Secondary
| Measure | Time frame |
|---|---|
| Fundus findings on OCT at start of HBOT, at session 11th, 21st, and 30th of HBOT, and at 2 weeks after the end of HBOT OCT Metrics,Diabetic retinopathy staging at start of HBOT, at session 11th, 21st, and 30th of HBOT, and at 2 weeks after the end of HBOT Fundus photograph | — |
Countries
Thailand
Contacts
Public ContactAsst. Prof.Supalert Prakhunhungsit
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed