Postmenopausal women isoflavone genistein serum topical postmenopausal
Conditions
Interventions
Topical isoflavone serum,Topical serum base
Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement
Sample,Placebo
Sponsors
Science and Technology Park, Chiang Mai University (STeP)
Faculty of Medicine, Chiang Mai University
Eligibility
Sex/Gender
Female
Age
48 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Postmenopausal women (48-65 years) who have no menstruation for at least 12 months 2. FSH >30 mU/mL 3. BMI = 18-30 kg/m2 4. Normal CBC, electrolytes, Liver and Renal function tests
Exclusion criteria
Exclusion criteria: 1. Person who is currently taking oestrogen hormone or isoflavone supplementation within 6 months of recruitment. 2. Person who is allergy to soy component. 3. Person who has a medical history of skin cancers or skin infection or any chronic diseases that contraindicated to soy products. 4. Person who uses other dietary supplement, herbals, vitamins and minerals, or any substance that affected their skin such as antibiotics, corticosteroids, or immunosuppressant agents within 3 month of recruitment. 4. Person who is alcohol drinking, smoking or recreational drug use.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Skin 0, 3 and 6 weeks Visiometer, Visiopore, Corneometer and Mexameter | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction week 3 and 6 satisfactory survey | — |
Countries
Thailand
Contacts
Public ContactMingkwan Na Takuathung
Department of Pharmacology, Faculty of Medicine, Chiang Mai University
Outcome results
None listed