Parkinson disease patients are suffered from motor and non-motor symptoms. Parkinson'
Conditions
Interventions
The cannabis oil (CBD:THC 1:1) were titrate with dose escalation schedule until achieved the satisfied effect for releasing Parkinson'
s symptoms. The maximum duration was 6 weeks. The evaluation of the response of treatment was done every 2 weeks.,The placebo was rice bran oil which had indistinguisable character by color and text
Active Comparator Drug,Placebo Comparator Drug
Cannabis oil (CBD:THC 1:1 mixture),Placebo
Sponsors
Department of Medical Services
Eligibility
Sex/Gender
All
Age
30 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Idiopathic parkinson's disease 2. Using stable doses of anti-Parkinson medication for atleast 30 days 3. Hoehn and Yahr stage 1-4
Exclusion criteria
Exclusion criteria: 1. Dementia 2. Psychiatric disorder 3. Ishcemic heart disease or cerebrovascular disease 4. Cannabis use within 30 days prior the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global score of parkinson symptoms Every 2 weeks until 6 weeks after end of intervention MDS-UPDRS | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor score of Parkinson disease Every 2 weeks until 6 weeksafter end of the intervention MDS-UPDRS part III,Motor complication score of Parkinson disesase Every 2 weeks until 6 weeks after end of the intervention MDS-UPDRS part IV,safety of the product use Every 2 weeks until 6 weeks after the intervention Interview | — |
Countries
Thailand
Contacts
Public ContactMintra Tangrungruengkit
Nopparat Rajathanee Hospital
Outcome results
None listed