Corneal epithelial defect healing after pterygium surgery Corneal epithelial defect healing, Corneal wound healing
Conditions
Interventions
Post-operative using 0.18% Sodium Hyaluronate eyedrops every 2 hours (8 times per day) for 3 days. Evaluate healing of epithelial defect before and after using the eyedrops.,Post-operative using 0.3%
Active Comparator Drug,Experimental Drug
0.18 percent Sodium Hyaluronate,0.3 percent Sodium Hyaluronate
Sponsors
Research Ethic Committee Faculty of medicine, Chiang Mai University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with post-operative primary pterygium excision with remaining corneal epithelial defect at 24 hours after surgery
Exclusion criteria
Exclusion criteria: 1. Other corneal diseases, 2. Limbal stem cells deficiency, 3. Eyelid deformities, 4. Systemic diseases affecting corneal wound healing ex. Sjogren's disease, Thyrotoxicosis, Diabetes Mellitus, 5. Currently taking systemic drugs affecting corneal wound healing ex. Isoretinoin within3 months prior to entering the trial, 6. History of eye surgery, 7. Glaucoma, 8. Having to use topical eyedrops everyday, 9. Ocular malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patient with epithelial defect closure 1, 2, 3 days Epithelial defect measurement using ImageJ program | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score 1, 2, 3 days Numerical pain score questionaires,Frequency of pain medication used 1, 2, 3 days Questionaires | — |
Countries
Thailand
Contacts
Public ContactWinai Chaidaroon
Faculty of Medicine, Chiang Mai University
Outcome results
None listed