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Comparison of postoperative pain between pethidine and paracetamol recipients with tibial fractures undergoing nailing surgery in Bahonar Hospital

Comparison of postoperative pain between pethidine and paracetamol recipients with tibial fractures undergoing nailing surgery in Bahonar Hospital

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210802005
Enrollment
96
Registered
2021-08-02
Start date
2021-05-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

compare the postoperative pain intensity between pethidine and paracetamol (Aptol) recipients with tibial fractures who underwent nailing surgery. pain, pethidine, paracetamol, fractures

Interventions

(1 mg / kg body weight) were injected half an hour before 6, 12 and 24 hours after surgery under local anesthesia.,paracetamol group (15 mg / kg body weight) were injected half an hour before 6, 12 an
Experimental Drug,Active Comparator Drug
pethidine group ,paracetamol group

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Patients with tibial fracture over 18 years of age and under 50 years of age who were candidates for tibial nail surgery. 2. Patients with tibial fracture who were classified into 42a, 42b and 42c groups according to AO classification.

Exclusion criteria

Exclusion criteria: 1. Any contraindications to paracetamol include liver disease and allergies 2. Any contraindications to the use of pethidine, including respiratory and drug-sensitive diseases. 3. If it is not possible to use the tibial nailing (such as fractures at the end and beginning of the tibia bone that cannot be nailed, or the tibial canal diameter is less than 8mm and thus, the nail cannot pass, or the tibia physe is open where nailing is forbidden). 4. Lack of consent to participate in the research project 5. Age over 50 years 6. Opium consumption 7. History of substance abuse (addicts) 8. People who received analgesics for any reason.

Design outcomes

Primary

MeasureTime frame
postoperative pain intensity 12 and 24 hours after surgery VAS scores

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Iran

Contacts

Public ContactFarzaneh Fazeli

Assistant Professor Of Intensive Care, North Khorasan University of Medical Sciences,Bojnord, Iran

Fazeli_farzaneh@yahoo.com983431325

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026