Primary osteoarthritis Primary osteoarthritis Ketorolac tromethamine Triamcinolone acetonide
Conditions
Interventions
Knee intraarticular injection with triamcinolone acetonide (40mg/1mL) 1 mL + 1% Lidocaine 3 mL ,Knee intraarticular injection with triamcinolone acetonide (40mg/1mL) 1 mL + 1% Lidocaine 3 mL + Ketorol
Active Comparator Drug,Active Comparator Drug
Group1 ,Group2
Sponsors
Faculty of medicine, prince of songkla university
Eligibility
Sex/Gender
All
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: 1 Age older than 45 years old 2 Patient who was diagnosed as primary osteoarthritis by ACR criteria with knee pain more than 3 months 3 Patient who were radiologically classified in Kellgren and Lawrence classification 2 or 3 4 VAS more than 4
Exclusion criteria
Exclusion criteria: 1 History of knee replacement or open knee surgery 2 Previous arthroscopic knee procedure within 6 months prior 3 Previous intraarticular injection within 3 months prior 4 Allergy of NSAIDs Corticosteroid and Lidocaine 5 Currently usage of anticoagulants corticosteroid and indomethacin 6 Patient with severely impaired cognitive function which is unable to evaluate outcomes and follow research protocol 7 Patient with severely illness such as poor controlled diabetes mellitus HbA1C more than 7.5% 8 Significant chronic kidney disease; GFR < 60 mL/minute within past 1 month 9 Patient who is currently or recently participating in any clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score at 1 and 3 month Visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional score at 1, 3 and 6 months KOOS score ,Pain score at 6 months Visual analog scale,Adverse effect at 1,3 and 6 months Questionnaire | — |
Countries
Thailand
Contacts
Public ContactKhanin Iamthanaporn
Prince of Songkla University
Outcome results
None listed