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Ganglion cell-inner plexiform layer thickness measured by Cirrus high-definition optical coherence tomography enhances glaucoma diagnosis in patients with moderate or high myopia

Ganglion cell-inner plexiform layer thickness in moderate and high myopic glaucomatous patients in Siriraj Hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20210726001
Enrollment
70
Registered
2021-07-26
Start date
2014-02-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma in moderate and high myopic patients. Glaucoma Myopia High myopia Moderate myopia Diagnostic procedures Ganglion Cell-Inner Plexiform Layer Thickness Spectral domain optical coherence tomography

Interventions

Non-glaucomatous subjects were defined as those with IOP less than 21 mmHg, no optic disc abnormalities, and the absence of visual field defect. Moderate myopia was defined by using spherical equivale
Moderately myopic, non-glaucomatous patients ,Highly myopic, non-glaucomatous patients ,Moderately myopic, glaucomatous patients ,Highly myopic, glaucomatous patients

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Best-corrected visual acuity (BCVA) 20/40 or better 2. Spherical equivalent less than or equal -3.0 diopters

Exclusion criteria

Exclusion criteria: 1. Subjects with retinal or macular pathology 2. Visual associated systemic or neurologic diseases 3. Received drugs with known side effects to macula eg. chloroquine ethambutol 4. Previous intraocular surgery or laser within 1 month 5. Inability to cooperated with the examination 6. Have allergic reaction to the eye drops used in the protocol

Design outcomes

Primary

MeasureTime frame
Ganglion cell-inner plexiform layer thickness After end of the intervention Cirrus spectral domain optical coherence tomography

Secondary

MeasureTime frame
Diagnostic abilities to detect glaucoma with optical coherence tomography in moderate and high myopic patients After end of the intervention Area under the receiver operating characteristic curve

Countries

Thailand

Contacts

Public ContactNgamkae Ruangvaravate

Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University

ngamkae1@gmail.com0818208610

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026