Chemotherapy induced neutropenia in solid cancer patients Chemotherapy induced neutropenia Monocyte count Neutrophil count
Conditions
Interventions
Patients with absolute neutrophil count less than 1500 cell/mm3 from complete blood count.
Diagnostic
Neutropenia patients
Sponsors
Medical oncology unit, Faculty of medicine, Chulalongkorn university
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - solid cancer patients with during chemotherapy any regimen in 2 or 3 week interval - first time of absolute neutrophil count less than 1500 cell/mm3 in day of next cycle or before 24 hour of next cycle - postpone chemotherapy by individual physician - patients can follow up complete blood count (CBC) in next 3 day - ECOG 0-2
Exclusion criteria
Exclusion criteria: - previous radiation within 30 days - bone marrow metastasis - receive prophylaxis granulocyte colony-stimulating factor (G-CSF) - receive systemic immunosuppressive medications - active infection - BMI less than 18.5 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil recovery next 3 days Proportion | — |
Secondary
| Measure | Time frame |
|---|---|
| Neutrophil recovery in patients with monocyte more than 15% next 3 days Proportion,Neutrophil recovery in patients with absolute monocyte count more than 400 cell/mm3 next 3 days Proportion,Relationship of monocyte count and neutrophil recovery next 3 days receiver operating characteristic curve (ROC) | — |
Countries
Thailand
Contacts
Public ContactPattarapon Yottasan
Faculty of medicine, Chulalongkorn university
Outcome results
None listed