Inpatients with acute kidney injury stage III, by definition KDIGO AKI 2012 , admit at King Chulalongkorn Memorial Hospital. MicroRNAs, Renal recovery, Renal non-recovery, Acute kidney injury
Conditions
Interventions
The participant with renal recovery should be alive and had serum creatinine less than 1.5 times the baseline level and had no renal replacement therapy.,the participant should have serum creatinine m
Prevention,Prevention
renal recovery ,renal non-recovery
Sponsors
The Kidney Foundation of Thailand, Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: The participant must be at age 18 years or above, has Acute kidney injury stage III, according to the definition of KDIGO AKI 2012, and has urine analysis with urine RBC less than 3/HPF, and urine WBC less than 3/HPF.
Exclusion criteria
Exclusion criteria: - CKD defined as persistent glomerular filtration rate < 60 mL/min/1.73m2 for at least 3 months. - Pregnancy - Advanced stage of cancer - Single kidney - Previous history of renal replacement therapy within 30 days - History of renal transplantation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Discovery of miRNA expressions in urine for predicting renal recovery after acute kidney injury. 2 years NanoString nCounter system assays in dicovery phase and qRT-PCR analysis in validation phase | — |
Secondary
| Measure | Time frame |
|---|---|
| Discovery of miRNA expressions in blood for predicting renal recovery after acute kidney injury. 2 years NanoString nCounter system assays in dicovery phase and qRT-PCR analysis in validation phase | — |
Countries
Thailand
Contacts
Public ContactThanawat phulkerd
chulalongkorn
Outcome results
None listed