healthy volunteers healthcare Workers
Conditions
Interventions
Participant received viral vector vaccine will be checked the antibody level at baseline before the first dose vaccination, before second dose, 4 weeks, 24 weeks and 48 weeks after complete vaccinatio
Experimental Biological/Vaccine,Active Comparator Biological/Vaccine
Viral vector vaccine,Inactivated vaccine
Sponsors
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Males or females at least 18 years of age (inclusive) 2. Be subject of study Seroprevalence, Incidence and Immunological Responses to SARS-CoV-2 Infection among Frontline Healthcare Workers compare with Non-COVID-19 HCWs during the COVID-19 Pandemic at Siriraj Hospital, Bangkok or healthcare workers who interested in receiving the vaccine in the study 3. Capable of informed consent and provision of written informed consent before any study procedures
Exclusion criteria
Exclusion criteria: 1. Could not receive vaccine such as history of anaphylaxis or severe infection with high temperature (over 38C) 2. Have received blood transfusion, plasma, blood product, blood components, immunoglobulins, antiviral or antibodies for treatment of COVID-19 within the last 90 days - Have detected COVID-19 infection within the last 10 days 3. Have unstable disease or could not control the symptom such as chest pain, dyspnea, palpitation, etc. 4. Be pregnant 5. Have history of immunodeficiency or use immunosuppressant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adverse events 48 week Proportion of participant with adverse events within 7 days after vaccination | — |
Secondary
| Measure | Time frame |
|---|---|
| Level of antibody response 48 week IgG level | — |
Countries
Thailand
Contacts
Public ContactNasikarn Angkasekwinai
Mahidol University
Outcome results
None listed