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A comparative study of high-frequency repetitive transcranial magnetic stimulation(rTMS) combined with treadmill training and treadmill training only on walking speed and balance in chronic stroke patients: a double-blind randomized controlled trial.

A comparative study of high-frequency repetitive transcranial magnetic stimulation(rTMS) combined with treadmill training and treadmill training only on walking speed and balance in chronic stroke patients: a double-blind randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210717001
Enrollment
30
Registered
2021-07-17
Start date
2021-12-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of rTMS combined with other neurorehabilitation therapies is increasing area of research interest. The effects on walking speed and balance which are crucial for independent ambulation in chronic stroke patients are still inconclusive. non-invasive neuromodulation, stroke, walking speed, balance, transcranial magnetic stimulation

Interventions

TMS combined treadmill training,sham TMS combined treadmill training
Active Comparator Device,Sham Comparator Other
TMS,sham TMS

Sponsors

Navamindradhiraj University, Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. First diagnosis of right hemiparesis secondary to stroke with right-handedness 2. Chronic stroke having an onset time longer than 6 months 3. Able to walk independently with or without devices 4. Montreal Cognitive Assessment score >10 (good to moderate cognitive impairment) 5. Electroencephalogram is no evidence of epileptic discharge 6. Participants should improve gait. 7. Age more than 18 years old

Exclusion criteria

Exclusion criteria: 1. Metal implants in the brain 2. Unstable medical condition 3. History of other disease known to interfere with study participation 4. History of seizure 5. No current use of antiepileptic medications for prevention of seizure 6. Severe communication problem

Design outcomes

Primary

MeasureTime frame
walking speed before pre-test, post-test and at 1-month follow-up. The GAITRite Electronic Walkway—

Secondary

MeasureTime frame
Balance before pre-test, post-test and at 1-month follow-up. Berg balance test,walking cadence before pre-test, post-test and at 1-month follow-up. The GAITRite Electronic Walkway ,Cognitive before pre-test, post-test and at 1-month follow-up. Montreal Cognitive Assessment,Double support before pre-test, post-test and at 1-month follow-up. The GAITRite Electronic Walkway,Spatial asymmetry ratio before pre-test, post-test and at 1-month follow-up. The GAITRite Electronic Walkway,Temporal asymmetry ratio before pre-test, post-test and at 1-month follow-up. The GAITRite Electronic Walkway—

Countries

Thailand

Contacts

Public ContactAnamon Tangjade

Navamindradhiraj University

Anamon@nmu.ac.th022443114

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026