acne/acneiform eruption induced by facial masks Delphini soothe and hydrate serum, acne, acneiform eruption, facial mask
Conditions
Interventions
Apply Delphini soothe and hydrate serum on the face and neck twice daily for 12 weeks.,Apply placebo serum without active ingredients on the face and neck twice daily for 12 weeks.
Experimental Drug,Placebo Comparator Drug
Delphini soothe and hydrate serum ,placebo serum without active ingredients
Sponsors
Faculty of Science, Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Both male and female participants aged 18-40 years with acne problems associated with wearing a mask by the following definitions: a) No history of acne treatment: Acne worsening after at least 6 weeks of using mask and physical examination revealed acne on the mask-covered areas. b) Being treated for acne: Acne breakouts after at least 6 weeks of using mask and physical examination revealed acne on the mask-covered areas. 2. Participants who were able to completely attend regular follow-up visits.
Exclusion criteria
Exclusion criteria: 1. Participants who are pregnancy or lactating 2. Participants with a history of allergy to the components of the product. 3. Participants who applied corticosteroids in the area to be tested within 2 weeks, received oral or intravenous corticosteroids within 4 weeks before testing 4. Participants who were underwent facial aesthetic procedures such as filler injection, lasers in the area of treatment within 3 months 5. Participants with a history of herpes simplex infection and active dermatitis within 3 months or a history of skin cancer. 6. Participants with rash or other skin diseases on the face that interfered with the evaluation of acne, such as seborrheic dermatitis, rosacea, etc. 7. Participants with Fitzpatrick skin type V-VI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of acne in each type week 0, 4, 8, 12 acne lesion counts,severity of acne week 0, 4, 8, 12 Leeds revised acne grading | — |
Secondary
| Measure | Time frame |
|---|---|
| skin hydration week 0, 4, 8, 12 Corneometry,skin evaporation week 0, 4,8, 12 Transepidermal water loss ,sebum levels week 0, 4, 8, 12 sebumeter,post acne erythema week 0, 4, 8, 12 photography by camera and Visia ,patient satisfaction week 0, 4, 8, 12 Patient Satisfaction Scale (PSS) ,rate of adversed event reported week 0, 4, 8, 12 number of events | — |
Countries
Thailand
Contacts
Public ContactChanat Kumtornrut
Faculty of Medicine, Chulalongkorn university
Outcome results
None listed