Healthy sodium hyaluronate, sodium ascorbyl phosphate, hyaluronic filler
Conditions
Interventions
Volunteers were injected with hyaluronic filler on both sides of the face. One side of face was treated with Eucerine hyaluron-filler first serum moisture booster apply bid after washing. Follow-up ef
Active Comparator Drug,Placebo Comparator Drug
Eucerine hyaluron-filler first serum moisture booster,Placebo
Sponsors
Galderma (Thailand)
Merz Aesthetics (Thailand) ,Beiersdorf (Thailand)
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Thai healthy volunteers aged equal to or more than 20 years 2. Patients who can come to follow up
Exclusion criteria
Exclusion criteria: 1. Patients who are pregnant, lactating, and postpartum within 3 months 2. Patients with history of hyaluronic acid allergy 3. Patients with other skin diseases, or having infection at the area of face 4. Immunocompromised patients 5. Patients treated with laser, radiofrequency, and focus ultrasound on the face in the past 12 months 6. Patients treated with filler on the face in the past 12 months 7. Patients treated with chemical peeling, treatment with vitamin C in the past 1 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin hydration Baseline, 2 weeks, 1, 2, and 3 months after treatment. Corneometer | — |
Secondary
| Measure | Time frame |
|---|---|
| indentation and maximum depth of wrinkle Baseline, 2 weeks, 1, 2, and 3 months after treatment. Antera analysis,Skin roughness Baseline, 2 weeks, 1, 2, and 3 months after treatment. Antera analysis,Physician improvement scale Baseline, 2 weeks, 1, 2, and 3 months after treatment. 6 points scale,Safety Baseline, 2 weeks, 1, 2, and 3 months after treatment. Adverse event | — |
Countries
Thailand
Contacts
Public ContactRungsima Wanitphakdeedecha
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed