Microbial contamination of multiple-dose preservative-free hospital ophthalmic preparations in a tertiary care hospital microbial contamination multiple dose eye drops anti-infective eye drops preservative-free hospital ophthalmic preparation
Conditions
Interventions
Eye drops samples in the study were cultured in chocolate agar, blood agar and sabouraud dextrose agar
Experimental Other
Eye drops samples cultured
Sponsors
Rajavithi Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients, regardless of diagnosis, who used topical anti-infective medications, preservative-free and multiple-use eye drops only, prepared by Rajavithi Hospital. The hospital-made preservative-free eye drops included: antibiotics Amikacin 50mg/ml, Ceftazidime 50mg/ml, Cefazolin 50mg/ml, Vancomycin 50mg/ml; antifungals Amphoterincin B 1.7mg/ml, Natamycin 50mg/ml, Voriconazole 10mg/ml.
Exclusion criteria
Exclusion criteria: Bottles used for fewer than 2 days or which had passed their expiry date were excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive culture 1 month Culture result from eye drops sample | — |
Secondary
| Measure | Time frame |
|---|---|
| factor related to contamination 1 month patients factor | — |
Countries
Thailand
Contacts
Public ContactSomporn Chantra
Rajavithi Hospital
Outcome results
None listed