Healthy female who schedule for open gynecologic surgery Gynecologic surgical procedure, Acute pain, Nerve block, Quadratus lumborum block
Conditions
Interventions
Regional anesthetic technique for abdominal surgery call Quadratus lumborum block or QL block. Local anesthetic will inject in front of QL muscle. ,Regional anesthetic technique for abdominal surgery
Anterior QLB,Posterior QLB,Control
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1 Patients with American Society of Anesthesiologists (ASA) physical classification I-III 2 Scheduled for elective open gynecologic surgeries which include total abdominal hysterectomy , total abdominal hysterectomy with bilateral salpingo-oophorectomy , myomectomy or ovarian cystectomy
Exclusion criteria
Exclusion criteria: 1 Patient who allergic local anesthetic or study drugs 2 Patient with chronic pain or chronic use of opioid (more than 2 weeks within 1-month 3 Patient who has local skin infection at injection site 4 Body mass index > 35 kg/m2 5 History of liver dysfunction (AST, ALT > 50 IU/L) or renal impairment (CrCl < 60 mg/ml), Coagulopathy (platelets < 100,000/mL or INR > 1.4) 6 Patient who cannot assess pain score or unable to operate intravenous-patient controlled analgesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 hours morphine consumption 1, 6, 12, 24 hours after surgery total mg of morphine | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score 1, 6, 12, 24 hours Numeric rating scale,Systemic concentration of bupivacaine 0, 15, 30, 60, 120, 240 min mcg/ml,Sensory loss 1, 6, 12, 24 hours after surgery Cold and pinprick sensation | — |
Countries
Thailand
Contacts
Public ContactSivaporn Thermpornlert
Ramathibodi hospital
Outcome results
None listed