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COST-UTILITY ANALYSIS OF ANTIBIOTICS COMPARED WITH OPERATIVE TREATMENT IN UNCOMPLICATED ACUTE APPENDICITIS

COST-UTILITY ANALYSIS OF ANTIBIOTICS COMPARED WITH OPERATIVE TREATMENT IN UNCOMPLICATED ACUTE APPENDICITIS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20210623005
Enrollment
226
Registered
2021-06-23
Start date
2019-12-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Most economic evidence has been generated from developed countries, with evidence from developing countries lacking, particularly using CUA from a societal perspective. As such, this study used real practice data to assess clinical effectiveness and CUA comparing individual antibiotics with appendectomy. This evidence will inform general surgeons in treatment management for uncomplicated acute appendicitis. Cost-utility appendicitis antibiotics appendectomy

Interventions

Two operative modalities (open and laparoscopic). laparoscopic was performed by single to three port incision and open was performed using McBurney point muscle-splitting incision immediately at the a
Treatment,Treatment
Operative treatment,Antibiotics treatment

Sponsors

Department of Clinical Epidemiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adult patients who were diagnosed with uncomplicated appendicitis (proven by ultrasonography or computer tomography)

Exclusion criteria

Exclusion criteria: Patients later diagnosed as complicated appendicitis were excluded

Design outcomes

Primary

MeasureTime frame
Cost 1 time at discharge date direct medical cost, direct non-medical and indirect costs

Secondary

MeasureTime frame
Utility 1. Before receiving treatment, 2. At discharge day, 3. At one week, 4. At one month European Quality of Life-5 Dimensions (EQ5D-5L)

Countries

Thailand

Contacts

Public ContactOraluck Pattanaprateep

Department of Clinical Epidemiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University

Oraluck.Pat@mahidol.edu022011269

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026